Genestra Brands - Berberis Formula 90 caps

EACH CAPSULE CONTAINS:

Barberry (Berberis vulgaris) Root and Stem Extract (4:1) . . 200mg 800 mg Dried Equivalent Oregon Grape (Mahonia aquifolium) Root Extract (4:1) (Mahonia aquifolium) (4:1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200mg 800 mg Dried Equivalent Goldenseal (Hydrastis canadensis) Root Std. Extract (10:1) (5% Alkaloids) (10:1) (5 % d’alcaloïdes) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50mg 500 mg Dried Equivalent Barberry (Berberis vulgaris) Root Bark . . . . . . . . . . . . . 25mg Oregon Grape (Mahonia aquifolium) Root . . . . . . 25mg Non-Medicinal Ingredients: Hypromellose, cellulose, silica

Combination of berberine extracts from natural plant sources
• Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative
• Includes goldenseal root extract, barberry root and stem extract, barberry root bark, Oregon grape root extract, and Oregon grape root

Berberis Formula is a blend of barberry, goldenseal and Oregon grape extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.^1,2 Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.³ Berberine also mediates the transport of ions and water across intestinal epithelial cells.³ It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3 Berberine can increase the expression of the Na+; H+ exchanger and aquaporin,² which help enhance the absorption of sodium and water, respectively.^3,4 Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.⁵ During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect._⁶