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Bioclinic - PEA (Palmitoylethanolamide) 400 mg - 90 Veg Capsules
SKU 9331
Bioclinic PEA (Palmitoylethanolamide) 400 mg 90 Veg Capsules
For chronic pain relief; Offers a natural source of PEA from non-GMO saffl ower oil; Micronized for improved bioavailability; Suitable for vegetarians and vegans.
Palmitoylethanolamide (PEA) is an endogenously produced lipid that mediates the resolution of neuroinflammation and clinically helps reduce pain from a variety of sources. PEA is a type of fatty acid ethanolamine produced in microglia and mast cells, where it downregulates the activation of both cell types; levels of PEA are increased in brain areas involved in nociception, and appear to modulate protective responses to both inflammation and pain. Its effects are mediated via direct activation of PPAR-a and GPR55 receptors, and potentially by indirect activation of CB1 and CB2 receptors and the TRPV1 channel (i.e., the capsaicin receptor).
PEA has helped to reduce pain levels from a variety of chronic conditions (of at least 6 months duration) where pain was not controlled by standard therapies, demonstrating effectiveness both alone and when combined with standard treatments. PEA has been shown to be efficacious for pain resulting from nerve compression syndromes, including sciatica and carpal tunnel syndrome. It has also being beneficial remedy to control pain related to specific conditions, including TMJ, as well as for depressive symptoms in major depressive disorder when used in conjunction with antidepressants.
In addition, PEA has been shown to improve endothelial function and reduce intraocular pressure among patients with ocular hypertension.
Ingredients:
| Each Capsule Contains: | |
| Palmitoylethanolamide (PEA) | 400 mg |
Non-Medicinal Ingredients: Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica, stearic acid.
Allergens & Purity: Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.
Recommended Adult Dose: 1 capsule 1–3 times per day or as directed by a health care practitioner.